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Fig. 4 | Genome Medicine

Fig. 4

From: Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations

Fig. 4

A Adult-onset asthma high-confidence candidate causal genes (N = 10), listed in descending order. The intensity of color shows the score contributed by each category. Nearest: variants whose nearest gene is the candidate gene; ABC: variants linked to the candidate gene by the ABC model; PCHi-C: variants linked to the candidate gene by PCHi-C; eQTL: variants linked to the candidate gene by eQTL; Exon: variants in the candidate gene’s exonic regions. The number in the parentheses indicates the number of variants linked to the corresponding gene. B Childhood-onset asthma high-confidence candidate causal genes (N = 35), listed in descending order. C Top Biological Processes GO terms enriched among AOA (top) and COA (bottom) high-confidence candidate causal genes, generated by WebGestalt’s weighted set cover algorithm

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Genome Medicine

ISSN: 1756-994X

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