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Fig. 4 | Genome Medicine

Fig. 4

From: Combining chromosome conformation capture and exome sequencing for simultaneous detection of structural and single-nucleotide variants

Fig. 4

Combination of Exo-C and nanopore sequencing enables detection of breakpoints with single-nucleotide resolution. A Assembly of Nanopore ligation libraries for WGS and adaptive sampling. B Enrichment of breakpoint regions with Cas9 utilizing a combination of tiling and nCATS approaches. C Comparison of coverage in breakpoint regions between different Nanopore library types (normalized for 1 Gb of data, coverage calculated for 5 kb bins). D Graphical representation of breakpoints detection by Exo-C, nanopore sequencing, and other methods

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Genome Medicine

ISSN: 1756-994X

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