Table 1 List of GWASs of neurodegenerative and psychiatric diseases
From: A multi-omic approach implicates novel protein dysregulation in post-traumatic stress disorder
Disease/disorders | Reference | Case | Control | N total | Loci identified | Ancestry group(s) and N of summary statistics used |
|---|---|---|---|---|---|---|
Autism spectrum disorder (ASD) | Grove et al. 2019 | 18,381 | 27,969 | 46,350 | 12 | All (EUR) |
Alzheimer’s disease (ALZ) | Wightman et al. 2021 | 90,338 | 1,036,225 | 1,126,563 | 38 | All (EUR/mixed) |
Bipolar disorder (BIP) | Mullins et al. 2021 | 41,917 | 371,549 | 413,466 | 64 | All (EUR) |
Major depressive disorder (MDD) | Meng et al. 2024 | 88,316 | 902,757 | 991,073 | 53 novel | All (multi-ancestry) |
Posttraumatic stress disorder (PTSD) | Nievergelt et al. 2024 | 150,760 | 1,130,173 | 1,280,933 | 95 | EUR (N = 1,222,882) |
Schizophrenia (SCZ) | Lam et al. 2019 | 56,418 | 78,818 | 135,236 | 19 | EUR (N = 77,096) |